Current Medical Diagnosis & Treatment 64Th Edition 2025

Current Medical Diagnosis & Treatment  64Th Edition 2025

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  Editors : 

Maxine A. Papadakis, MD

Professor of Medicine, EmeritusDepartment of MedicineUniversity of California, San Francisco

Michael W. Rabow, MD

Professor of Medicine and UrologyDivision of Palliative MedicineDepartment of MedicineUniversity of California, San Francisco

Kenneth R. McQuaid, MD

Professor of MedicineDepartment of MedicineUniversity of California, San Francisco

Monica Gandhi, MD, MPH

Professor of MedicineDivision of HIV, ID, and Global MedicineSan Francisco General HospitalUniversity of California, San Francisco

  Pages: 1857

 Language: English

 Format: PDF

 Size: 59

Contents :

1. Disease Prevention & Health Promotion 1Michael Pignone, MD, MPH2. Common Symptoms 15Paul L. Nadler, MD, &Ralph Gonzales, MD, MSPH3. Preoperative Evaluation & PerioperativeManagement 42Hugo Q. Cheng, MD4. Geriatric Disorders 52Leah J. Witt, MD, Rossana Lau-Ng, MD, &G. Michael Harper, MD5. Palliative Care & Pain Management 69Michael W. Rabow, MD, Kara E. Bischoff, MD,Ann Cai Shah, MD, Lawrence Poree, MD, MPH, PhD,& Karin Sinavsky, MD, MS6. Dermatologic Disorders 101Nathan W. Rojek, MD, Scott Worswick, MD,Kanade Shinkai, MD, PhD, & Lindy P. Fox, MD7. Disorders of the Eyes & Lids 166Jacque L. Duncan, MD, Neeti B. Parikh, MD, &Gerami D. Seitzman, MD8. Otolaryngology Disorders 200Elliott D. Kozin, MD, Rosh Sethi, MD, &Lawrence R. Lustig, MD9. Pulmonary Disorders 242Rime Abbas, MD, Mazen El Ali, MD,Meghan E. Fitzpatrick, MD, &Belinda Rivera-Lebron, MD, MS, FCCP10. Coronary Artery Disease, Valvular Disease,& Other Key Topics in Cardiology 316Todd Kiefer, MD11. Heart Failure & Cardiomyopathy 390Christopher B. Granger, MD12. Disorders of Cardiac Rhythm 410Kevin P. Jackson, MD13. Systemic Hypertension 431Michael Sutters, MD, MRCP (UK)14. Blood Vessel & Lymphatic Disorders 460Warren J. Gasper, MD, James C. Iannuzzi, MD, MPH,& Meshell D. Johnson, MD15. Blood Disorders 488Lloyd E. Damon, MD, &Charalambos Babis Andreadis, MD, MSCE16. Disorders of Hemostasis, Thrombosis, &Antithrombotic Therapy 534Andrew D. Leavitt, MD, &Erika Leemann Price, MD, MPH17. Gastrointestinal Disorders 568Kenneth R. McQuaid, MD18. Liver, Biliary Tract, & PancreasDisorders 665Lawrence S. Friedman, MD19. Breast Disorders 726Armando E. Giuliano, MD, FACS, FRCSEd, &Sara A. Hurvitz, MD, FACP20. Gynecologic Disorders 752Jill Brown, MD, MPH, MHS, FACOG, &Katerina Shvartsman, MD, FACOG21. Obstetrics & Obstetric Disorders 783

22. Rheumatologic, Immunologic, &Allergic Disorders 809Rebecca L. Manno, MD, MHS,Jinoos Yazdany, MD, MPH,Teresa K. Tarrant, MD, & Mildred Kwan, MD, PhD

23. Electrolyte & Acid-Base Disorders 864Nayan Arora, MD, & J. Ashley Jefferson, MD, FRCP24. Kidney Disease 893Tonja C. Dirkx, MD, & Tyler B. Woodell, MD, MCR25. Urologic Disorders 931Mathew Sorensen, MD, MS, FACS,Marah C. Hehemann, MD, &Maahum A. Haider, MD, MPH26. Nervous System Disorders 958Vanja C. Douglas, MD, &Michael J. Aminoff, MD, DSc, FRCP27. Psychiatric Disorders 1035Kristin S. Raj, MD, Nolan R. Williams, MD,Charles DeBattista, DMH, MD, &Meshell D. Johnson, MD28. Endocrine Disorders 1085Paul A. Fitzgerald, MD29. Diabetes Mellitus & Hypoglycemia 1179Umesh Masharani, MB, BS30. Lipid Disorders 1223Michael J. Blaha, MD, MPH31. Nutrition, Nutritional Disorders, &Obesity 1235Katherine H. Saunders, MD,Leon I. Igel, MD, FACP, FTOS, &Sarah Fink, RD, CDN, CNSC32. Common Problems in InfectiousDiseases & Antimicrobial Therapy 1255Monica Fung, MD, MPH, Katherine Gruenberg,PharmD, MAEd, & Peter V. Chin-Hong, MD33. HIV Infection & AIDS 1297Monica Gandhi, MD, MPH, &Matthew A. Spinelli, MD, MAS34. Viral & Rickettsial Infections 1338Eva H. Clark, MD, PhD, Patrycja Ashley, MD, &Wayne X. Shandera, MD35. Bacterial & Chlamydial Infections 1429Kelly A. Johnson, MD, MPH, &Emma D. Bainbridge, MD, MPH36. Spirochetal Infections 1470Susan S. Philip, MD, MPH37. Protozoal & Helminthic Infections 1487Philip J. Rosenthal, MD38. Mycotic Infections 1523Stacey R. Rose, MD, FACP, FIDSA, &Richard J. Hamill, MD, FACP, FIDSA39. Disorders Related to EnvironmentalEmergencies 1537Jacqueline A. Nemer, MD, FACEP, &Marianne A. Juarez, MD40. Poisoning 1553Craig Smollin, MD41. Cancer 1583Sunny Wang, MD, Tiffany O. Dea, PharmD, BCOP,Lawrence S. Friedman, MD, Carling Ursem, MD,Kenneth R. McQuaid, MD, & Marc A. Dall’Era, MD42. Genetic & Genomic Disorders 1647Reed E. Pyeritz, MD, PhD43. Orthopedic Disorders &Sports Medicine 1657Anthony Luke, MD, MPH, & C. Benjamin Ma, MD44. Sexual & Gender Minority Health 1693Patricia A. Robertson, MD, Nicole Rosendale, MD,Kevin L. Ard, MD, MPH, Kenneth H. Mayer, MD,& Mitzi Hawkins, MD, MAS45. Substance Use Disorders 1715J. Janet Ho, MD, MPH, FASAM,Julian A. Mitton, MD, MPH, & Jessica Ristau, MDCONTENTS

The following chapters are available onlinewithout subscription atwww.accessmedicine.com/CMDTe1. Anti-infective Treatment: Antibiotic,Antifungal, and Antiviral AgentsKatherine Gruenberg, PharmD, MAEd, &Emily Kaip, PharmDe2. Diagnostic Testing & MedicalDecision-MakingChuanyi Mark Lu, MDe3. Information Technology inPatient CareRuss Cucina, MD, MSe4. Podiatric DisordersMonara Dini, DPM, & Charles B. Parks, DPMe5. Women’s Health IssuesBrigid M. Dolan, MD, MEd, &Judith Walsh, MD, MPHe6. Appendix: Therapeutic DrugMonitoring, Laboratory ReferenceIntervals, & Commonly Used BloodSpecimen Collection TubesChuanyi Mark Lu, MD

Index.

   Preface                                       

CURRENT Medical Diagnosis & Treatment 2025 (CMDT 2025) is the 64th edition of this single-source reference for practitionersof adult medicine in both hospital and ambulatory settings. The book emphasizes the practical features of clinicaldiagnosis and patient management in all fields of internal medicine and in specialties of interest to primary care practitionersand to subspecialists who provide general care.With a growing recognition of systemic racism and other biases in institutions across our societies, including the institutionof medicine (https://www.mdcalc.com/race), the editors of CMDT, with humility, have committed to a thoroughexamination of our content to remove biased language, research, and recommendations. Since 2020, we have been pursuingan ongoing, formal process of review and revision in an effort to recognize and correct biases and to promote equity in ourbook and thus in the practice of medicine. While we, the editors, take this on as our responsibility, we also invite readers toshare with us any CMDT content that they find problematic or biased. Please email comments to CMDT@mheducation.com.We have tried to describe populations used in the studies that form the basis of the information in CMDT and use appropriatelanguage where we can (eg, persons of sub-Sahara African descent, rather than African Americans). We continue,however, to use terms from original sources when study populations are broad.

INTENDED AUDIENCE FOR CMDT

House officers, medical students, and all other health professions learners will find the descriptions of diagnostic andtherapeutic modalities, with citations to the current literature, of everyday usefulness in patient care.Internists, family physicians, hospitalists, nurse practitioners, physician associates, and all primary care providers ofadult medicine will appreciate CMDT as a ready reference and refresher text. Physicians in other specialties, pharmacists,and dentists will find the book a useful basic medical reference text. Nurses, nurse practitioners, and physician associateswill welcome the format and scope of the book as a means of quickly referencing medical diagnosis and treatmentmodalities.Patients and their family members who seek information about the nature of specific diseases and their diagnosis andtreatment may also find this book to be a valuable resource.

NEW IN THIS EDITION OF CMDT

The “Year in Review: Key Clinical Updates in CMDT 2025” highlights what the editors consider to be the most significantclinical changes over the last year, providing page numbers and reference citations for easy access. This tool ismeant to get users “current” quickly but does not reflect all the changes since the last edition.

OUTSTANDING FEATURES OF CMDT

• Medical advances up to time of annual publication• Detailed presentation of internal medicine disciplines, plus key primary care topics• At-a-glance format, facilitating efficient use in any practice setting• Coverage of more than 1000 diseases and disorders• Specific disease prevention information• Easy access to medication dosages, with trade names indexed and updated in each annual edition• Recent references, with unique identifiers (PubMed, PMID numbers) for rapid downloading of article abstracts and, insome instances, full-text reference articles

BONUS E-CHAPTERS, CMDT ON ACCESSMEDICINE

Six e-chapters listed in the Table of Contents can be accessed at www.AccessMedicine.com/CMDT. These online-onlychapters (available without the need for subscription) include• Anti-Infective Chemotherapeutic & Antibiotic Agents• Diagnostic Testing & Medical Decision-Making• Information Technology in Patient Care• Podiatric Disorders• Women’s Health Issues• Appendix: Therapeutic Drug Monitoring, Laboratory Reference Intervals, & Commonly Used Blood SpecimenCollection Tubes

                           

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