Target Volume Defnition in Radiation Oncology by Anca-Ligia Grosu,Carsten Nieder,Nils Henrik Nicolay Second Edition 2023
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Editors :
Anca-Ligia Grosu
Department of Radiation Oncology
Medical Center, University of Freiburg
Freiburg im Breisgau, BadenWürttemberg, Germany
Nils Henrik Nicolay
Department of Radiation Oncology
University of Leipzig Medical Center
Leipzig, Germany
Carsten Nieder
Department of Oncology
Nordland Hospital
Bodo, Norway
Pages: 462
Language: English
Format: PDF
Size:34.2 MB
Contents
Brain Gliomas of Adulthood
Ilinca Popp, Oliver Oehlke, Carsten Nieder,
and Anca-Ligia Grosu
2 Brain Metastases .
Carsten Nieder and Laurie E. Gaspar
3 Spinal Cord Tumors
Michael H. Wang, Jay Detsky, Christopher D. Witiw,
Ashish Kumar, Mary Jane Lim-Fat, Julia Keith,
Pejman Maralani, Simon S. Lo, and Arjun Sahgal
4 Base of the Skull and Orbit
Carsten Nieder, Sabrin
a T. Astner, Tobias Boeckh-Behrens,
and Claire Delbridge
5 Head and Neck Cancer
Alexander Rühle and Nils H. Nicolay
6 Lung Cancer
Eleni Gkika, Sonja Adebahr, Tanja Schimek-Jasch,
and Ursula Nestle
7 Esophageal Cancer
Thomas B. Brunner and Frank Zimmermann
8 Gastric Cancer
Francesco Cellini, Calogero Casà , Andrea D’Avier and Vincenzo Valentini
9 Pancreatic Cancer
Thomas B. Brunner, Eleni Gkika, and Daniel Schanne
10 Liver Tumours
Eleni Gkika, Daniel Schanne, and Thomas B. Brunner
11 Rectal Cancer
Emmanouil Fokas, Cihan Gani, Vincenzo Valentini,
Claus Rödel, and Maria Antonietta Gambacorta
12 Anal Carcinoma
Mark Harrison, Vicky Goh, Ajay Aggarwal, Hendi Maher,
Suraiya Dubash, Robert Hughes, and Rob Glynne-Jones
13 Gynecological Cancer
Nina A. Mayr, Larissa J. Lee, William Small Jr,
and Catheryn M. Yashar
14 Prostate Cancer
Constantinos Zamboglou and Simon Kirste
15 Bone Metastases
Robert Förster and Tanja Sprave
16 Sarcomas
Michael S. Rutenberg and Daniel J. Indelicato
17 Lymphomas
Colin E. Champ and Christopher R. Kelsey
18 Breast Cancer
Stefanie Corradini, David Krug, Jan Haussmann,
Christiane Matuschek, and Juliane Hörner-Rieber
19 Bladder Cancer
Alexander Fabian, Justus Domschikowski, Jürgen Dunst,
and Oliver J. Ott
Index .
Preface
The history of radiation therapy for malignant diseases dates back throughout
almost the complete twentieth century. Neither three-dimensional crosssectional imaging, such as computed tomography or magnetic resonance
imaging, nor functional imaging, such as positron-emission tomography
(PET), was available during the frst decades. This resulted in treatment planning approaches that most of today’s radiation oncologists are completely
unfamiliar with. One particular example highlighting the development in a
highly radio-curable malignancy is Hodgkin’s lymphoma. Compared to historical extended-feld radiotherapy based on bony landmarks defning the
feld borders, we have witnessed the introduction of involved feld and
involved node radiotherapy, as well as PET-guided or -adapted treatment
selection algorithms. Our ability to account for organ motion during treatment delivery has changed the way of administering radiation to the lung and
mediastinum. Simultaneously, evolution of image-guided and high-precision
application technology has outperformed clinicians’ ability to precisely
defne the clinical target volume (CTV) in a number of diseases. Practicing
radiation oncologists have to make several important decisions during treatment planning and realization, one patient at a time. It all starts with staging,
multidisciplinary discussion, and volume delineation, in case radiotherapy is
indicated and recommended. It would be of limited or no value to precisely
deliver the prescribed treatment to an incorrectly defned CTV. Artifcial
intelligence and deep learning are starting to impact the diagnostic and treatment planning processes and are likely to modify several parts of the present
workfow.
The purpose of this book is to provide practicing radiation oncologists and
therapists, as well as those in training, with a concise overview of the most
important and up-to-date information pertaining to target volume defnition.
Several chapters, e.g., those dealing with lymphoma, sarcoma, and spine/spinal cord malignancies, not only include common clinical scenarios but also
present challenging cases and rare cancer types. The issue of interobserver
variability is addressed, and when available, the reader is introduced to consensus guidelines. The latter have evolved signifcantly after publication of
the frst edition of this textbook in 2015. Therefore, a completely updated
second edition had to be prepared.
We are most grateful for the enthusiasm and courtesy all chapter authors
showed during preparation of this truly international volume and for the fruitful discussion with many colleagues. The SARS-CoV-2 pandemic hasunfortunately delayed the preparation of this second edition. Eventually, all
contributors managed to deliver their up-to-date chapters. We also appreciate
the excellent long-term support from the publisher. We hope that the reader
will fnd this book to be a useful summary of current knowledge. Only continued cooperative research will provide a better basis for tolerable and effcacious treatment regimens, exploiting the promises put forward by the
emerging concepts of personalized, ablative, and adaptive radiation therapy.
